A simplified but equally accurate C-13 urea breath test for Helicobacter pylori

The urea breath test for Helicobacter pylori.

[Validation of a simplified 13C-urea breath test method for the diagnosis of Helicobacter pylori infection].

OBJECTIVE To validate a simplified 13C-urea breath test (13C-UBT) method for the diagnosis of H. pylori infection. MATERIAL AND METHODS Patients referred for gastrointestinal endoscopy and biopsy were included, and a 13C-UBT was performed after a 6-hour fast. Breath samples were collected in 10 ml glass tubes before and 30 min after the simultaneous administration of 50 mg of 13C-urea and 2 g...

Diagnosis of Helicobacter pylori by carbon-13 urea breath test using a portable mass spectrometer

CONTEXT In the non-invasive detection of markers of disease, mass spectrometry is able to detect small quantities of volatile markers in exhaled air. However, the problem of size, expense and immobility of conventional mass spectrometry equipment has restricted its use. Now, a smaller, less expensive, portable quadrupole mass spectrometer system has been developed. Helicobacter pylori has been ...

Does low dose (13)C-urea breath test maintain a satisfactory accuracy in diagnosing Helicobacter pylori infection?

CONTEXT The standard doses of (13)C-urea in (13)C-urea breath test is 75 mg. OBJECTIVE To assess the diagnostic accuracy of (13)C-urea breath test containing 25 mg of (13)C-urea comparing with the standard doses of 75 mg in the diagnosis of Helicobacter pylori infection. METHODS Two hundred seventy adult patients (96 males, 174 females, median age 41 years) performed the standard (13)C-urea...

Appropriate Timing of the C-Urea Breath Test to Establish Eradication of Helicobacter pylori Infection

METHODS: Patients with active Helicobacter pylori infection at four medical centers received proton pump inhibitorbased triple or quadruple therapy for 10–14 days. Patients underwent the C-UBT 2 and 4–6 wk after the completion of therapy. A positive test was defined as CO2 excretion of .200 dpm, a negative test as ,50 dpm, and an equivocal test as .50 but ,200 dpm. Performance characteristics o...